Coronavirus learned to enter a cell without the ACE2 enzyme

American scientists said that due to mutations, the coronavirus will enter the human body faster.

The first species of SARS-CoV-2 used a spike protein to cling to ACE2 (an enzyme on the surface of the cell). Now the ACE2 receptors viruses are not needed. This was found out in the course of experiments that were carried out at the University of Washington, writes RIA Novosti with reference to the resource

At first, scientists used primate kidney cells. And then they took human lung cancer cells (they do not have the ACE2 enzyme – ed.). And the new strain grown in the laboratory was able to get into them bypassing the standard scheme.

“It was an incredible surprise for us,” said one of the study participants. He added that it has not yet been established whether such a mutation is possible outside the laboratory. But one thing is clear – the virus is looking for new ways to enter cells.

The director of the Gamaleya Center, Alexander Gintsburg, previously said that with a radical change in the genome of the virus, the composition of the COVID-19 vaccine would have to be updated. “If vector technology is registered, then we can really respond to a newly emerging threat within a week,” he said.


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